All Publications

2023 - Istaroxime Metabolite PST3093 Selectively Stimulates SERCA2a and Reverses Disease-Induced Changes in Cardiac Function: Arici, M., Ferrandi, M., Barassi, P., Hsu, S., Torre, E., Luraghi, A., et al. (2023). Istaroxime Metabolite PST3093 Selectively Stimulates SERCA2a and Reverses Disease-Induced Changes in Cardiac Function. THE JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 384(1), 231-244 [10.1124/jpet.122.001335].2023 - Microbiota-Derived Natural Products Targeting Cancer Stem Cells: Inside the Gut Pharma Factory: Artusa, V., Calabrone, L., Mortara, L., Peri, F., Bruno, A. (2023). Microbiota-Derived Natural Products Targeting Cancer Stem Cells: Inside the Gut Pharma Factory. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24(5) [10.3390/ijms24054997].2023 - New Glucosamine-Based TLR4 Agonists: Design, Synthesis, Mechanism of Action, and In Vivo Activity as Vaccine Adjuvants: Romerio, A., Gotri, N., Franco, A., Artusa, V., Shaik, M., Pasco, S., et al. (2023). New Glucosamine-Based TLR4 Agonists: Design, Synthesis, Mechanism of Action, and In Vivo Activity as Vaccine Adjuvants. JOURNAL OF MEDICINAL CHEMISTRY, 66(4), 3010-3029 [10.1021/acs.jmedchem.2c01998].2023 - Potentiation of fluoroquinolone and macrolide activities by efflux pump inhibitory effect on Staphylococcus aureus and Streptococcus pyogenes of new benzyl piperazinyl lysine derivatives: Musumeci, R., Martinelli, M., Giubbi, C., Perdoni, F., Romerio, A., Vertemara, J., et al. (2023). Potentiation of fluoroquinolone and macrolide activities by efflux pump inhibitory effect on Staphylococcus aureus and Streptococcus pyogenes of new benzyl piperazinyl lysine derivatives. Intervento presentato a: 33rd ECCMID. European Congress of Clinical Microbiology and Infectious Diseases, Copenhagen, Danimarca.2023 - Emerging Extracellular Molecular Targets for Innovative Pharmacological Approaches to Resistant Mtb Infection: Italia, A., Shaik, M., Peri, F. (2023). Emerging Extracellular Molecular Targets for Innovative Pharmacological Approaches to Resistant Mtb Infection. BIOMOLECULES, 13(6) [10.3390/biom13060999].2022 - Green and Roasted Coffee Extracts Inhibit Interferon-β Release in LPS-Stimulated Human Macrophages: Artusa, V., Ciaramelli, C., D’Aloia, A., Facchini, F., Gotri, N., Bruno, A., et al. (2022). Green and Roasted Coffee Extracts Inhibit Interferon-β Release in LPS-Stimulated Human Macrophages. FRONTIERS IN PHARMACOLOGY, 13 [10.3389/fphar.2022.806010].2022 - Highly Selective SERCA2a Activators: Preclinical Development of a Congeneric Group of First-in-Class Drug Leads against Heart Failure: Luraghi, A., Ferrandi, M., Barassi, P., Arici, M., Hsu, S., Torre, E., et al. (2022). Highly Selective SERCA2a Activators: Preclinical Development of a Congeneric Group of First-in-Class Drug Leads against Heart Failure. JOURNAL OF MEDICINAL CHEMISTRY, 65(10), 7324-7333 [10.1021/acs.jmedchem.2c00347].2022 - A Global Picture of Molecular Changes Associated to LPS Treatment in THP-1 Derived Human Macrophages by Fourier Transform Infrared Microspectroscopy: Ami, D., Franco, A., Artusa, V., Mereghetti, P., Peri, F., Natalello, A. (2022). A Global Picture of Molecular Changes Associated to LPS Treatment in THP-1 Derived Human Macrophages by Fourier Transform Infrared Microspectroscopy. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 23(21) [10.3390/ijms232113447].2021 - Developing New Anti-Tuberculosis Vaccines: Focus on Adjuvants: Franco, A., Peri, F. (2021). Developing New Anti-Tuberculosis Vaccines: Focus on Adjuvants. CELLS, 10(1), 1-17 [10.3390/cells10010078].2021 - The Multi-Level Mechanism of Action of a Pan-Ras Inhibitor Explains its Antiproliferative Activity on Cetuximab-Resistant Cancer Cells: Tisi, R., Spinelli, M., Palmioli, A., Airoldi, C., Cazzaniga, P., Besozzi, D., et al. (2021). The Multi-Level Mechanism of Action of a Pan-Ras Inhibitor Explains its Antiproliferative Activity on Cetuximab-Resistant Cancer Cells. FRONTIERS IN MOLECULAR BIOSCIENCES, 8(17 February 2021) [10.3389/fmolb.2021.625979].2021 - Synthetic glycolipid-based TLR4 antagonists negatively regulate TRIF-dependent TLR4 signalling in human macrophages: Palmer, C., Facchini, F., Jones, R., Neumann, F., Peri, F., Pirianov, G. (2021). Synthetic glycolipid-based TLR4 antagonists negatively regulate TRIF-dependent TLR4 signalling in human macrophages. INNATE IMMUNITY, 27(3), 275-284 [10.1177/17534259211005840].2021 - A Highly Sensitive Luminescent Biosensor for the Microvolumetric Detection of the Pseudomonas aeruginosa Siderophore Pyochelin: Visaggio, D., Pirolo, M., Frangipani, E., Lucidi, M., Sorrentino, R., Mitidieri, E., et al. (2021). A Highly Sensitive Luminescent Biosensor for the Microvolumetric Detection of the Pseudomonas aeruginosa Siderophore Pyochelin. ACS SENSORS, 6(9), 3273-3283 [10.1021/acssensors.1c01023].2021 - Synthetic Glycolipids as Molecular Vaccine Adjuvants: Mechanism of Action in Human Cells and in Vivo Activity: Facchini, F., Minotti, A., Luraghi, A., Romerio, A., Gotri, N., Matamoros-Recio, A., et al. (2021). Synthetic Glycolipids as Molecular Vaccine Adjuvants: Mechanism of Action in Human Cells and in Vivo Activity. JOURNAL OF MEDICINAL CHEMISTRY, 64(16), 12261-12272 [10.1021/acs.jmedchem.1c00896].2021 - Electrospinning for drug delivery applications: A review: Luraghi, A., Peri, F., Moroni, L. (2021). Electrospinning for drug delivery applications: A review. JOURNAL OF CONTROLLED RELEASE, 334, 463-484 [10.1016/j.jconrel.2021.03.033].2020 - Effect of chemical modulation of toll-like receptor 4 in an animal model of ulcerative colitis: Facchini, F., Di Fusco, D., Barresi, S., Luraghi, A., Minotti, A., Granucci, F., et al. (2020). Effect of chemical modulation of toll-like receptor 4 in an animal model of ulcerative colitis. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 76(3), 409-418 [10.1007/s00228-019-02799-7].2020 - The Role of TLR4 in Neural Stem Cells–Mediated Neurogenesis and Neuroinflammation: De Filippis, L., Peri, F. (2020). The Role of TLR4 in Neural Stem Cells–Mediated Neurogenesis and Neuroinflammation. In The Role of Toll-Like Receptor 4 in Infectious and Non Infectious Inflammation (pp. 129-141). Birkhaeuser Science [10.1007/978-3-030-56319-6_9].2020 - Increasing the Chemical Variety of Small-Molecule-Based TLR4 Modulators: An Overview: Romerio, A., Peri, F. (2020). Increasing the Chemical Variety of Small-Molecule-Based TLR4 Modulators: An Overview. FRONTIERS IN IMMUNOLOGY, 11 [10.3389/fimmu.2020.01210].2020 - Microbiome studies in the medical sciences and the need for closer multidisciplinary interplay: Mancini, N., Peri, F., Rescigno, M., Zanoni, I. (2020). Microbiome studies in the medical sciences and the need for closer multidisciplinary interplay. SCIENCE SIGNALING, 13(617) [10.1126/scisignal.aba9911].2019 - Structural characterization of aerogels derived from enzymatically oxidized galactomannans of fenugreek, sesbania and guar gums: Ponzini, E., Natalello, A., Usai, F., Bechmann, M., Peri, F., Müller, N., et al. (2019). Structural characterization of aerogels derived from enzymatically oxidized galactomannans of fenugreek, sesbania and guar gums. CARBOHYDRATE POLYMERS, 207, 510-520 [10.1016/j.carbpol.2018.11.100].2019 - Novel carboxylate-based glycolipids: TLR4 antagonism, MD-2 binding and self-assembly properties: Cochet, F., Facchini, F., Zaffaroni, L., Billod, J., Coelho, H., Holgado, A., et al. (2019). Novel carboxylate-based glycolipids: TLR4 antagonism, MD-2 binding and self-assembly properties. SCIENTIFIC REPORTS, 9(1) [10.1038/s41598-018-37421-w].2019 - Synthesis of the New Cyanine-Labeled Bacterial Lipooligosaccharides for Intracellular Imaging and in Vitro Microscopy Studies: Wang, T., Cochet, F., Facchini, F., Zaffaroni, L., Serba, C., Pascal, S., et al. (2019). Synthesis of the New Cyanine-Labeled Bacterial Lipooligosaccharides for Intracellular Imaging and in Vitro Microscopy Studies. BIOCONJUGATE CHEMISTRY, 30(6), 1649-1657 [10.1021/acs.bioconjchem.9b00044].2018 - Dye-Sensitized Photocatalytic Hydrogen Generation: Efficiency Enhancement by Organic Photosensitizer-Coadsorbent Intermolecular Interaction: Manfredi, N., Monai, M., Montini, T., Peri, F., De Angelis, F., Fornasiero, P., et al. (2018). Dye-Sensitized Photocatalytic Hydrogen Generation: Efficiency Enhancement by Organic Photosensitizer-Coadsorbent Intermolecular Interaction. ACS ENERGY LETTERS, 3(1), 85-91 [10.1021/acsenergylett.7b00896].2018 - Co-administration of Antimicrobial Peptides Enhances Toll-like Receptor 4 Antagonist Activity of a Synthetic Glycolipid: Peri, F., Facchini, F., Coelho, H., Sestito, S., Delgado, S., Minotti, A., et al. (2018). Co-administration of Antimicrobial Peptides Enhances Toll-like Receptor 4 Antagonist Activity of a Synthetic Glycolipid. CHEMMEDCHEM, 13(3), 280-287 [10.1002/cmdc.201700694].2018 - Toll-like receptor 4 modulation influences human neural stem cell proliferation and differentiation: Grasselli, C., Ferrari, D., Zalfa, C., Soncini, M., Mazzoccoli, G., Facchini, F., et al. (2018). Toll-like receptor 4 modulation influences human neural stem cell proliferation and differentiation. CELL DEATH & DISEASE, 9(3) [10.1038/s41419-017-0139-8].2018 - Recent advances on Toll-like receptor 4 modulation: new therapeutic perspectives: Zaffaroni, L., Peri, F. (2018). Recent advances on Toll-like receptor 4 modulation: new therapeutic perspectives. FUTURE MEDICINAL CHEMISTRY, 10(4), 461-476 [10.4155/fmc-2017-0172].2018 - Structure–Activity Relationship in Monosaccharide-Based Toll-Like Receptor 4 (TLR4) Antagonists: Facchini, F., Zaffaroni, L., Minotti, A., Rapisarda, S., Calabrese, V., Forcella, M., et al. (2018). Structure–Activity Relationship in Monosaccharide-Based Toll-Like Receptor 4 (TLR4) Antagonists. JOURNAL OF MEDICINAL CHEMISTRY, 61(7), 2895-2909 [10.1021/acs.jmedchem.7b01803].2018 - The synthetic glycolipid-based TLR4 antagonist FP7 negatively regulates in vitro and in vivo haematopoietic and non-haematopoietic vascular TLR4 signalling: Palmer, C., Peri, F., Neumann, F., Ahmad, F., Leake, D., Pirianov, G. (2018). The synthetic glycolipid-based TLR4 antagonist FP7 negatively regulates in vitro and in vivo haematopoietic and non-haematopoietic vascular TLR4 signalling. INNATE IMMUNITY, 24(7), 411-421 [10.1177/1753425918798904].2018 - Structure and inflammatory activity of the LPS isolated from Acetobacter pasteurianus CIP103108: Pallach, M., Di Lorenzo, F., Facchini, F., Gully, D., Giraud, E., Peri, F., et al. (2018). Structure and inflammatory activity of the LPS isolated from Acetobacter pasteurianus CIP103108. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 119, 1027-1035 [10.1016/j.ijbiomac.2018.08.035].2018 - Toll-like receptor 4-induced glycolytic burst in human monocyte-derived dendritic cells results from p38-dependent stabilization of HIF-1a and increased hexokinase II Expression: Perrin-Cocon, L., Aublin-Gex, A., Diaz, O., Ramiere, C., Peri, F., Andre, P., et al. (2018). Toll-like receptor 4-induced glycolytic burst in human monocyte-derived dendritic cells results from p38-dependent stabilization of HIF-1a and increased hexokinase II Expression. JOURNAL OF IMMUNOLOGY, 201(5), 1510-1521 [10.4049/jimmunol.1701522].2017 - TLR4 antagonist FP7 inhibits LPS-induced cytokine production and glycolytic reprogramming in dendritic cells, and protects mice from lethal influenza infection: Perrin Cocon, L., Aublin Gex, A., Sestito, S., Shirey, K., Patel, M., André, P., et al. (2017). TLR4 antagonist FP7 inhibits LPS-induced cytokine production and glycolytic reprogramming in dendritic cells, and protects mice from lethal influenza infection. SCIENTIFIC REPORTS, 7 [10.1038/srep40791].2017 - Amphiphilic Guanidinocalixarenes Inhibit Lipopolysaccharide (LPS)-and Lectin-Stimulated Toll-like Receptor 4 (TLR4) Signaling: Sestito, S., Facchini, F., Morbioli, I., Billod, J., Martin Santamaria, S., Casnati, A., et al. (2017). Amphiphilic Guanidinocalixarenes Inhibit Lipopolysaccharide (LPS)-and Lectin-Stimulated Toll-like Receptor 4 (TLR4) Signaling. JOURNAL OF MEDICINAL CHEMISTRY, 60(12), 4882-4892 [10.1021/acs.jmedchem.7b00095].2017 - The role of carbohydrates in the lipopolysaccharide (LPS)/toll-like receptor 4 (TLR4) Signalling: Cochet, F., Peri, F. (2017). The role of carbohydrates in the lipopolysaccharide (LPS)/toll-like receptor 4 (TLR4) Signalling. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 18(11) [10.3390/ijms18112318].2017 - TLR4 signaling pathway modulators as potential therapeutics in inflammation and sepsis: Kuzmich, N., Sivak, K., Chubarev, V., Porozov, Y., Savateeva-Lyubimova, T., Peri, F. (2017). TLR4 signaling pathway modulators as potential therapeutics in inflammation and sepsis. VACCINES, 5(4) [10.3390/vaccines5040034].2017 - How do viruses interfere with Toll-like receptor 4?: Perrin-Cocon, L., Peri, F., Lotteau, V. (2017). How do viruses interfere with Toll-like receptor 4?. FUTURE VIROLOGY, 12(6), 243-246 [10.2217/fvl-2017-0030].2016 - Dye-sensitized photocatalytic hydrogen production: Distinct activity in a glucose derivative of a phenothiazine dye: Manfredi, N., Cecconi, B., Calabrese, V., Minotti, A., Peri, F., Ruffo, R., et al. (2016). Dye-sensitized photocatalytic hydrogen production: Distinct activity in a glucose derivative of a phenothiazine dye. CHEMICAL COMMUNICATIONS, 52(43), 6977-6980 [10.1039/c6cc00390g].2016 - Synthetic and natural small molecule TLR4 antagonists inhibit motoneuron death in cultures from ALS mouse model: De Paola, M., Sestito, S., Mariani, A., Memo, C., Fanelli, R., Freschi, M., et al. (2016). Synthetic and natural small molecule TLR4 antagonists inhibit motoneuron death in cultures from ALS mouse model. PHARMACOLOGICAL RESEARCH, 103, 180-187 [10.1016/j.phrs.2015.11.020].2016 - The EuroSciCon's 2015 Innate Immunity Summit: Camprubí Rimblas, M., Peri, F., Mcknight, Á., Matteucci, C., Guillamat Prats, R. (2016). The EuroSciCon's 2015 Innate Immunity Summit. FUTURE VIROLOGY, 11(10), 665-669 [10.2217/fvl-2016-0091].2016 - Glycolipid-based TLR4 Modulators and Fluorescent Probes: Rational Design, Synthesis, and Biological Properties: Ciaramelli, C., Calabrese, V., Sestito, S., Pérez Regidor, L., Klett, J., Oblak, A., et al. (2016). Glycolipid-based TLR4 Modulators and Fluorescent Probes: Rational Design, Synthesis, and Biological Properties. CHEMICAL BIOLOGY & DRUG DESIGN, 88(2), 217-229 [10.1111/cbdd.12749].2016 - Structure-Activity Studies on Arylamides and Arysulfonamides Ras Inhibitors: Colombo, S., Palmioli, A., Airoldi, C., Tisi, R., Fantinato, S., Olivieri, S., et al. (2016). Structure-Activity Studies on Arylamides and Arysulfonamides Ras Inhibitors. In B.S.P. Atta-ur-Rahman (a cura di), Advances in Cancer Drug Targets (pp. 245-264). Bentham Science Publishers [10.2174/97816810823321160301].2015 - Chemistry of lipid a: At the heart of innate immunity: Molinaro, A., Holst, O., Lorenzo, F., Callaghan, M., Nurisso, A., D'Errico, G., et al. (2015). Chemistry of lipid a: At the heart of innate immunity. CHEMISTRY-A EUROPEAN JOURNAL, 21(2), 500-519 [10.1002/chem.201403923].2015 - A novel small molecule TLR4 antagonist (IAXO-102) negatively regulates non-hematopoietic toll like receptor 4 signalling and inhibits aortic aneurysms development: Huggins, C., Pearce, S., Peri, F., Neumann, F., Cockerill, G., Pirianov, G. (2015). A novel small molecule TLR4 antagonist (IAXO-102) negatively regulates non-hematopoietic toll like receptor 4 signalling and inhibits aortic aneurysms development. ATHEROSCLEROSIS, 242(2), 563-570 [10.1016/j.atherosclerosis.2015.08.010].2015 - Molecular simplification of lipid A structure: TLR4-modulating cationic and anionic amphiphiles: Calabrese, V., Cighetti, R., Peri, F. (2015). Molecular simplification of lipid A structure: TLR4-modulating cationic and anionic amphiphiles. MOLECULAR IMMUNOLOGY, 63(2), 153-161 [10.1016/j.molimm.2014.05.011].2015 - Editorial: Peri, F., Granucci, F., Weiss, J. (2015). Editorial. MOLECULAR IMMUNOLOGY, 63(2), 125-126 [10.1016/j.molimm.2014.09.001].2014 - Clicked and long spaced galactosyl- and lactosylcalix[4]arenes: New multivalent galectin-3 ligands: Bernardi, S., Fezzardi, P., Rispoli, G., Sestito, S., Peri, F., Sansone, F., et al. (2014). Clicked and long spaced galactosyl- and lactosylcalix[4]arenes: New multivalent galectin-3 ligands. BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY, 10, 1672-1680 [10.3762/bjoc.10.175].2014 - Modulation of CD14 and TLR4·MD-2 activities by a synthetic lipid A mimetic: Cighetti, R., Ciaramelli, C., Sestito, S., Zanoni, I., Kubik, Ł., Ardá Freire, A., et al. (2014). Modulation of CD14 and TLR4·MD-2 activities by a synthetic lipid A mimetic. CHEMBIOCHEM, 15(2), 250-258 [10.1002/cbic.201300588].2014 - Toll-like Receptor 4 (TLR4) Modulation by Synthetic and Natural Compounds: An Update: Peri, F., Calabrese, V. (2014). Toll-like Receptor 4 (TLR4) Modulation by Synthetic and Natural Compounds: An Update. JOURNAL OF MEDICINAL CHEMISTRY, 57(9), 3612-3622 [10.1021/jm401006s].2014 - Functional characterization of E. coli LptC: Interaction with LPS and a synthetic ligand: Sestito, S., Sperandeo, P., Santambrogio, C., Ciaramelli, C., Calabrese, V., Rovati, G., et al. (2014). Functional characterization of E. coli LptC: Interaction with LPS and a synthetic ligand. CHEMBIOCHEM, 15(5), 734-742 [10.1002/cbic.201300805].2014 - Trehalose- and glucose-derived glycoamphiphiles: Small-molecule and nanoparticle toll-like receptor 4 (TLR4) modulators: Rodriguez Lavado, J., Sestito, S., Cighetti, R., Aguilar Moncayo, E., Oblak, A., Lainšček, D., et al. (2014). Trehalose- and glucose-derived glycoamphiphiles: Small-molecule and nanoparticle toll-like receptor 4 (TLR4) modulators. JOURNAL OF MEDICINAL CHEMISTRY, 57(21), 9105-9123 [10.1021/jm501182w].2013 - Clustered carbohydrates in synthetic vaccines: Peri, F. (2013). Clustered carbohydrates in synthetic vaccines. CHEMICAL SOCIETY REVIEWS, 42(11), 4543-4556 [10.1039/c2cs35422e].2013 - Sugar-Based Inhibitors of Ras Activation: Biological Activity and Identification of Ras–Inhibitor Binding Interface: Di Domizio, A., Peri, F. (2013). Sugar-Based Inhibitors of Ras Activation: Biological Activity and Identification of Ras–Inhibitor Binding Interface. In The Enzymes, Inhibitors of the Ras Superfamily G-proteins, Part A (pp. 95-116). F. Tamanoi [10.1016/B978-0-12-416749-0.00005-1].2013 - A new isoluminol reagent for chemiluminescence labeling of proteins: Palmioli, A., Crisma, M., Peggion, C., Brusasca, P., Zanin, D., Dal Corso, A., et al. (2013). A new isoluminol reagent for chemiluminescence labeling of proteins. TETRAHEDRON LETTERS, 54(33), 4446-4450 [10.1016/j.tetlet.2013.06.036].2013 - Multivalent glycoconjugates as anti-pathogenic agents: Bernardi, A., Jiménez Barbero, J., Casnati, A., De Castro, C., Darbre, T., Fieschi, F., et al. (2013). Multivalent glycoconjugates as anti-pathogenic agents. CHEMICAL SOCIETY REVIEWS, 42(11), 4709-4727 [10.1039/C2CS35408J].2012 - Synthetic molecules and functionalized nanoparticles targeting the LPS-TLR4 signaling: a new generation of immunotherapeutics: Peri, F., Calabrese, V., Piazza, M., Cighetti, R. (2012). Synthetic molecules and functionalized nanoparticles targeting the LPS-TLR4 signaling: a new generation of immunotherapeutics. PURE AND APPLIED CHEMISTRY, 84(1), 97-106 [10.1351/PAC-CON-11-10-35].2012 - Metabolism of Phosphatidylinositol 4-Kinase IIIα-Dependent PI4P Is Subverted by HCV and Is Targeted by a 4-Anilino Quinazoline with Antiviral Activity: Bianco, A., Alvarez, R., Fenu, S., Reghellin, V., Baruffa, C., Peri, F., et al. (2012). Metabolism of Phosphatidylinositol 4-Kinase IIIα-Dependent PI4P Is Subverted by HCV and Is Targeted by a 4-Anilino Quinazoline with Antiviral Activity. PLOS PATHOGENS, 8(3), 1-17 [10.1371/journal.ppat.1002576].2012 - Compound for the covalent attachment of the chemiluminescent probe N-(4-Aminobutyl)-N-ethylisoluminol (ABEI) to target molecules and uses thereof: Peri, F., Palmioli, A., Cummings, S., Olson, G. (2012)Compound for the covalent attachment of the chemiluminescent probe N-(4-Aminobutyl)-N-ethylisoluminol (ABEI) to target molecules and uses thereof. . Brevetto No. EP20100014657 20101116.2012 - A Synthetic Lipid A Mimetic Modulates Human TLR4 Activity: Peri, F., Piazza, M., Cighetti, R., Damore, G., Calabrese, V., Weiss, J., et al. (2012). A Synthetic Lipid A Mimetic Modulates Human TLR4 Activity. CHEMMEDCHEM, 7(2), 213-217 [10.1002/cmdc.201100494].2012 - Therapeutic targeting of innate immunity with Toll-like receptor 4 (TLR4) antagonists: Peri, F., Piazza, M. (2012). Therapeutic targeting of innate immunity with Toll-like receptor 4 (TLR4) antagonists. BIOTECHNOLOGY ADVANCES, 30(1), 251-260 [10.1016/j.biotechadv.2011.05.014].2012 - Chemoselective glycosylation techniques for the synthesis of bioactive neoglycoconjugates, glyconanoparticles and glycoarrays: Peri, F. (2012). Chemoselective glycosylation techniques for the synthesis of bioactive neoglycoconjugates, glyconanoparticles and glycoarrays. In Chemoselective glycosylation techniques for the synthesis of bioactive neoglycoconjugates, glyconanoparticles and glycoarrays (pp. 203-225). Olivier Renaudet.2011 - Optimizing operating conditions and electrochemical characterization of glucose–gluconate alkaline fuel cells: Pasta, M., La Mantia, F., Ruffo, R., Peri, F., Della Pina, C., Mari, C. (2011). Optimizing operating conditions and electrochemical characterization of glucose–gluconate alkaline fuel cells. JOURNAL OF POWER SOURCES, 196(3), 1273-1278 [10.1016/j.jpowsour.2010.08.018].2011 - Binding properties and biological characterization of new sugar-derived Ras ligands: Sacco, E., Abraham, S., Palmioli, A., Damore, G., Bargna, A., Mazzoleni, E., et al. (2011). Binding properties and biological characterization of new sugar-derived Ras ligands. MEDCHEMCOMM, 2(5), 396-401 [10.1039/C0MD00264J].2011 - Carbohydrate-based bioactive compounds for medicinal chemistry applications: Cipolla, L., Peri, F. (2011). Carbohydrate-based bioactive compounds for medicinal chemistry applications. MINI-REVIEWS IN MEDICINAL CHEMISTRY, 11(1), 39-54 [10.2174/138955711793564060].2011 - Uniform Lipopolysaccharide (LPS)-Loaded Magnetic Nanoparticles for the Investigation of LPS–TLR4 Signaling: Piazza, M., Colombo, M., Zanoni, I., Granucci, F., Tortora, P., Weiss, J., et al. (2011). Uniform Lipopolysaccharide (LPS)-Loaded Magnetic Nanoparticles for the Investigation of LPS–TLR4 Signaling. ANGEWANDTE CHEMIE. INTERNATIONAL EDITION, 50(3), 622-626 [10.1002/anie.201004655].2011 - Hemin and a metabolic derivative coprohemin modulate the TLR4 pathway differently through different molecular targets: Piazza, M., Damore, G., Costa, B., Gioannini, T., Weiss, J., Peri, F. (2011). Hemin and a metabolic derivative coprohemin modulate the TLR4 pathway differently through different molecular targets. INNATE IMMUNITY, 17(3), 293-301 [10.1177/1753425910369020].2011 - Modulation of LPS signaling through TLR4 agonists and antagonists: Peri, F., Cighetti, R., Piazza, M., Calabrese, V. (2011). Modulation of LPS signaling through TLR4 agonists and antagonists. In Bacterial Lipopolysacchardies (pp. 389-416). springer [10.1007/978-3-7091-0733-1_13].2010 - Exploring the LPS/TLR4 signal pathway with small molecules: Peri, F., Piazza, M., Calabrese, V., Damore, G., Cighetti, R. (2010). Exploring the LPS/TLR4 signal pathway with small molecules. BIOCHEMICAL SOCIETY TRANSACTIONS, 38(5), 1390-1395 [10.1042/BST0381390].2010 - The cationic amphiphile 3,4-bis (tetradecyloxy) benzylamine inhibits LPS signaling by competing with endotoxin for CD14 binding: Piazza, M., Calabrese, V., Baruffa, C., Gioannini, T., Weiss, J., Peri, F. (2010). The cationic amphiphile 3,4-bis (tetradecyloxy) benzylamine inhibits LPS signaling by competing with endotoxin for CD14 binding. BIOCHEMICAL PHARMACOLOGY, 80(12), 2050-2056 [10.1016/j.bcp.2010.06.019].2010 - Structure-Activity Studies on Arylamides and Arysulfonamides Ras Inhibitors: Colombo, S., Palmioli, A., Airoldi, C., Tisi, R., Fantinato, S., Olivieri, S., et al. (2010). Structure-Activity Studies on Arylamides and Arysulfonamides Ras Inhibitors. CURRENT CANCER DRUG TARGETS, 10(2), 192-199 [10.2174/156800910791054185].2009 - Glycolipids and benzylammonium lipids as novel antisepsis agents: Synthesis and biological characterization: Piazza, M., Rossini, C., Della Fiorentina, S., Pozzi, C., Comelli, F., Bettoni, I., et al. (2009). Glycolipids and benzylammonium lipids as novel antisepsis agents: Synthesis and biological characterization. JOURNAL OF MEDICINAL CHEMISTRY, 52(4), 1209-1213 [10.1021/jm801333m].2009 - Evidence of a specific interaction between new synthetic antisepsis agents and CD14: Piazza, M., Yu, L., Teghanemt, A., Gioannini, T., Weiss, J., Peri, F. (2009). Evidence of a specific interaction between new synthetic antisepsis agents and CD14. BIOCHEMISTRY, 48(51), 12337-12344 [10.1021/bi901601b].2009 - Design, Synthesis and Biological Evaluation of Levoglucosenone-derived Ras Activation Inhibitors: Müeller, C., Gomez Zurita Frau, M., Ballinari, D., Colombo, S., Bitto, A., Martegani, E., et al. (2009). Design, Synthesis and Biological Evaluation of Levoglucosenone-derived Ras Activation Inhibitors. CHEMMEDCHEM, 4, 524-528 [10.1002/cmdc.200800416].2009 - First experimental identification of Ras-inhibitor binding interface using a water-soluble Ras ligand: Palmioli, A., Sacco, E., Abraham, S., Thomas, C., DI DOMIZIO, A., DE GIOIA, L., et al. (2009). First experimental identification of Ras-inhibitor binding interface using a water-soluble Ras ligand. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 19(15), 4217-4222 [10.1016/j.bmcl.2009.05.107].2009 - Selective cytotoxicity of a bicyclic Ras inhibitor in cancer cells expressing K-RasG13D: Palmioli, A., Sacco, E., Airoldi, C., Di Nicolantonio, F., D'Urzo, A., Shirasawa, S., et al. (2009). Selective cytotoxicity of a bicyclic Ras inhibitor in cancer cells expressing K-RasG13D. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 386(4), 593-597 [10.1016/j.bbrc.2009.06.069].2008 - Glial TLR4 receptor as new target to treat neuropathic pain: efficacy of a new receptor antagonist in a model of peripheral nerve injury in mice: Bettoni, I., Comelli, F., Rossini, C., Granucci, F., Giagnoni, G., Peri, F., et al. (2008). Glial TLR4 receptor as new target to treat neuropathic pain: efficacy of a new receptor antagonist in a model of peripheral nerve injury in mice. GLIA, 56(12), 1312-1319 [10.1002/glia.20699].2008 - Glycoconjugates in cancer therapy: Cipolla, L., Peri, F., Airoldi, C. (2008). Glycoconjugates in cancer therapy. ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 8(1), 92-121 [10.2174/187152008783330815].2007 - The bone morphogenic protein antagonist Drm/gremlin is a novel pro- angiogenic factor: Stabile, H., Mitola, S., Moroni, E., Belleri, M., Nicoli, S., Coltrini, D., et al. (2007). The bone morphogenic protein antagonist Drm/gremlin is a novel pro- angiogenic factor. BLOOD, 109(5), 1834-1840 [10.1182/blood-2006-06-032276].2007 - Novel α-conotoxin from Conus spurius and the α-conotoxin EI share high-affinity potentiation and low-affinity inhibition of nicotinic acetylcoline receptors: Lopez Vera, E., Aguilar, M., Schiavon, E., Marinzi, E., Ortiz, E., Restano Cassulini, R., et al. (2007). Novel α-conotoxin from Conus spurius and the α-conotoxin EI share high-affinity potentiation and low-affinity inhibition of nicotinic acetylcoline receptors. THE FEBS JOURNAL, 274(15), 3972-3985 [10.1111/j.1742-4658.2007.05931.x].2007 - Inhibition of lipid A stimulated activation of human dendritic cells and macrophages by amino and hydroxylamino monosaccharides: Peri, F., Granucci, F., Costa, B., Zanoni, I., Marinzi, C., Nicotra, F. (2007). Inhibition of lipid A stimulated activation of human dendritic cells and macrophages by amino and hydroxylamino monosaccharides. ANGEWANDTE CHEMIE. INTERNATIONAL EDITION, 46(18), 3308-3312 [10.1002/anie.200604932].2006 - Sugar-derived Ras inhibitors: group epitope mapping by NMR spectroscopy and biological evaluation: Peri, F., Airoldi, C., Colombo, S., Mari, S., Jiménez Barbero, J., Martegani, E., et al. (2006). Sugar-derived Ras inhibitors: group epitope mapping by NMR spectroscopy and biological evaluation. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2006(16), 3707-3720 [10.1002/ejoc.200600132].2007 - Chemoselective neoglycosylation: Nicotra, F., Cipolla, L., Peri, F., LA FERLA, B., Redaelli, C. (2007). Chemoselective neoglycosylation. ADVANCES IN CARBOHYDRATE CHEMISTRY AND BIOCHEMISTRY, 61, 353-398 [10.1016/S0065-2318(07)61007-5].2007 - Glucose-derived Ras pathway inhibitors: evidence of Ras-ligand binding and Ras-GEF (Cdc25) interaction inhibition: Airoldi, C., Palmioli, A., D'Urzo, A., Colombo, S., Vanoni, M., Martegani, E., et al. (2007). Glucose-derived Ras pathway inhibitors: evidence of Ras-ligand binding and Ras-GEF (Cdc25) interaction inhibition. CHEMBIOCHEM, 8(12), 1376-1379 [10.1002/cbic.200700185].2006 - Looking forward: A glance into the future of organic chemistry: Compain, P., Desvergnes, V., Ollivier, C., Robert, F., Suzenet, F., Barboiu, M., et al. (2006). Looking forward: A glance into the future of organic chemistry. NEW JOURNAL OF CHEMISTRY, 30(6), 823-831 [10.1039/B601837H].2006 - Synthesis and biological evaluation of novel lipid A antagonists: Peri, F., Marinzi, C., Barath, M., Granucci, F., Urbano, M., Nicotra, F. (2006). Synthesis and biological evaluation of novel lipid A antagonists. BIOORGANIC & MEDICINAL CHEMISTRY, 14(1), 190-199 [10.1016/j.bmc.2005.08.047].2006 - Bicyclic carbohydrate-derived scaffolds for combinatorial libraries: Cervi, G., Peri, F., Gennari, C., Battistini, C., Nicotra, F. (2006). Bicyclic carbohydrate-derived scaffolds for combinatorial libraries. BIOORGANIC & MEDICINAL CHEMISTRY, 14(10), 3349-3367 [10.1016/j.bmc.2005.12.055].2006 - Lipid A antagonists with anti-septic shock, anti-inflammatory, anti-ischemia and analgesic activity: Peri, F., Nicotra, F., Granucci, F., Costa, B. (2006)Lipid A antagonists with anti-septic shock, anti-inflammatory, anti-ischemia and analgesic activity. . Brevetto No. MI2006A000530.2005 - Carbohydrate Scaffolds for the Production of Bioactive Compounds: Cipolla, L., Peri, F., LA FERLA, B., Redaelli, C., Nicotra, F. (2005). Carbohydrate Scaffolds for the Production of Bioactive Compounds. CURRENT ORGANIC SYNTHESIS, 2(2), 153-173 [10.2174/1570179053545341].2005 - Design, synthesis and biological evaluation of sugar-derived Ras inhibitors: Peri, F., Airoldi, C., Colombo, S., Martegani, E., van Neuren, A., Stein, M., et al. (2005). Design, synthesis and biological evaluation of sugar-derived Ras inhibitors. CHEMBIOCHEM, 6(10), 1839-1848 [10.1002/cbic.200400420].2004 - Synthesis of imino sugar scaffolds for the generation of glycosidase inhibitor libraries: LA FERLA, B., Bugada, P., Cipolla, L., Peri, F., Nicotra, F. (2004). Synthesis of imino sugar scaffolds for the generation of glycosidase inhibitor libraries. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2004(11), 2451-2470 [10.1002/ejoc.200300805].2005 - Studies on the mechanism of action of a new class of inhibitors of Ras activation: Colombo, S., Tisi, R., Airoldi, C., Peri, F., Nicotra, F., Martegani, E. (2005). Studies on the mechanism of action of a new class of inhibitors of Ras activation. Intervento presentato a: IUBMB 50th Anniversary Symposium - 2 - 7 July, Budapest, Hungary.2004 - Design and characterisation of a new class of inhibitors of Ras activation: Colombo, S., Peri, F., Tisi, R., Nicotra, F., Martegani, E. (2004). Design and characterisation of a new class of inhibitors of Ras activation. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1030, 52-61 [10.1196/annals.1329.007].2004 - Synthesis and conformational analysis of novel N(OCH3) disaccharide analogues: Peri, F., Jiménez Barbero, J., García Aparicio, V., Tvaroska, I., Nicotra, F. (2004). Synthesis and conformational analysis of novel N(OCH3) disaccharide analogues. CHEMISTRY-A EUROPEAN JOURNAL, 10(6), 1433-1444 [10.1002/chem.200305587].2004 - Chemoselective Ligation in Glycochemistry: Peri, F., Nicotra, F. (2004). Chemoselective Ligation in Glycochemistry. CHEMICAL COMMUNICATIONS, 4(6), 623-627 [10.1039/B308907J].2003 - Rigid polycycles and peptidomimetics from carbohydrate synthons: Peri, F., Cipolla, L., LA FERLA, B., Forni, E., Caneva, E., DE GIOIA, L., et al. (2003). Rigid polycycles and peptidomimetics from carbohydrate synthons. In Z.J. Witczak1, K. Tatsuta (a cura di), Carbohydrate Synthons in Natural products Chemistry; Synthesis, Functionalization, and Applications-ACS-Symposium Series (pp. 141-156). USA : ACS.2003 - Glycoconjugate and oligosaccharide mimetics by chemoselective ligation: Peri, F., Cipolla, L., LA FERLA, B., Nicotra, F. (2003). Glycoconjugate and oligosaccharide mimetics by chemoselective ligation. COMPTES RENDUS CHIMIE, 6(7), 635-644 [10.1016/S1631-0748(03)00122-X].2003 - Fused oxabicyclic aminoalcohols as new scaffolds for combinatorial libraries: Peri, F., Nicotra, F., Gennari, C., Battistini, C. (2003)Fused oxabicyclic aminoalcohols as new scaffolds for combinatorial libraries. . Brevetto No. EP20030100991.2002 - Arabinose-derived Bicyclic Amino Acids: Synthesis, Conformational Analysis and Construction of an avb3-selective RGD Peptide: Peri, F., Bassetti, R., Caneva, E., DE GIOIA, L., LA FERLA, B., Presta, M., et al. (2002). Arabinose-derived Bicyclic Amino Acids: Synthesis, Conformational Analysis and Construction of an avb3-selective RGD Peptide. JOURNAL OF THE CHEMICAL SOCIETY. PERKIN TRANSACTIONS. 1, 2002(5), 368-644 [10.1039/b110453e].2002 - Solution and solid-phase chemoselective synthesis of (1-6)-amino(methoxy) di- and trisaccharide analogues: Peri, F., Deutman, A., LA FERLA, B., Nicotra, F. (2002). Solution and solid-phase chemoselective synthesis of (1-6)-amino(methoxy) di- and trisaccharide analogues. CHEMICAL COMMUNICATIONS, 14(14), 1504-1505 [10.1039/b203605c].2003 - Conformational features of a synthetic model of the first extracellular loop of the angiotensin II AT1A receptor: Nicastro, G., Peri, F., Franzoni, L., De Chiara, C., Sartor, G., Spisni, A. (2003). Conformational features of a synthetic model of the first extracellular loop of the angiotensin II AT1A receptor. JOURNAL OF PEPTIDE SCIENCE, 9, 229-243.2003 - D-glucose as a regioselectively addressable scaffold for combinatorial chemistry on solid phase: Peri, F., Leslie, C., Micheli, F., Seneci, P., Marchioro, C., Nicotra, F. (2003). D-glucose as a regioselectively addressable scaffold for combinatorial chemistry on solid phase. JOURNAL OF CARBOHYDRATE CHEMISTRY, 22(1), 57-71 [10.1081/CAR-120019014].2003 - Extending chemoselective ligation to sugar chemistry:convergent assembly of bioactive neoglycoconjugates: Peri, F. (2003). Extending chemoselective ligation to sugar chemistry:convergent assembly of bioactive neoglycoconjugates. MINI-REVIEWS IN MEDICINAL CHEMISTRY, 3(7), 651-658 [10.2174/1389557033487700].