TLR4 as an important target in SARS-COV2 therapy
Rationale COVID-19 may present with mild, moderate, or severe illness. The severe clinical manifestations include severe pneumonia, Acute Respiratory Syndrome (ARDS), sepsis, and septic shock (Cascella M, Rajnik M, Cuomo A, et al. Features, Evaluation and Treatment Coronavirus (COVID-19) [Updated 2020 Mar 8]. In: StatPearls-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK554776/). While the virus itself is only moderately pathogenic and about 50% of infected individuals barely notice (“a bad flu”). The others suffer from
