Francesco Peri

University of Milano-Bicocca

Department of Biotechnology and Biosciences



Rector's delegate for the foundation University for Innovation (u4i)

Rector's delegate for the Calro Erba foundtation

President of the MicrobiotaMi association


Francesco Peri

Academic positions
2017-present Full professor, Organic Chemistry, Department of Biotechnology and Biosciences, University of Milano-Bicocca
2009- present professorship at the Ecole Normale Supérieure (ENS), Lyon, France
2012 Visiting Professor, UC Davis, graduate course “Advanced Organic Synthesis” Chem231B
2012 Professorship at Paris 5 University, Chemistry at the interface with biology.
2012 National habilitation to Full professor in Organic Chemistry
2007-2017 Associate Professor, Department of Biotechnology and Biosciences, University of Milano-Bicocca
2002-2007 Assistant Professor, Department of Biotechnology and Biosciences, University of Milano-Bicocca
1999-2001 Post-doctoral fellowship, University of Milano-Bicocca in collaboration with GlaxoWellcome (Verona, Italy)
1996-1998 Post-doctoral fellowship, PhD Univerity of Lausanne (Switzerland)

Francesco Peri metrics and publications (Google Scholar)


The research activity of F. Peri lab is focused in the development of new drug leads and in the study of biological pathways by means of small molecules.

The main research line is aimed at developing new small molecular drug hits, active in modulating the activity of the Toll Like Receptor 4 (TLR4) in the perspective to develop new generations of TLR-directed therapeutics.

This has been the focus of the H2020-funded MSCA-ETN project TOLLerant (GA number 642157) that F. Peri coordinated from 2015 to 2018.

In this context, new TLR4 agonists will be developed as vaccine adjuvants, within the MSCA-ETN project BactiVax (2019-2022).

Another research line is based on the development of new synthetic steroids able to activate selectively the human SERCA2a protein (in collaboration with other academic and industrial groups).

Funding and grants

2010-2011: Unit coordinator of PRIN grant from Italian Ministry of University and Research (MIUR), title of the project: New multivalent ligands for human galectins as diagnostic and therapeutic agents (3 years grant, 130.000 E for the research unit)

2009-2014:Unit coordinator in the NIH grant AI 59372 “Regulation of MD-2 function and expression”, in collaboration with J. Weiss and T. Gioannini (University of Iowa) (5 years, 50.000 E/year )

2010-2013: Unit coordinator in NEDD grant, design on novel pharmaceutically active compounds (80.000E, 2 years).

2013-2016: Unit coordinator of PRIN grant from Italian Ministry of University and Research (MIUR), title of the project: “Italian network for the development of multivalent nanosystems (MULTINANOITA)” (3 years grant, 53.000 E for the research unit)

2015-2018: Coordinator of Horizon 2020-funded MSCA-ETN project TOLLerant “Toll like Receptor 4 activation and function in diseases: an integrated chemical biology approach”, Grant Agreement number 642157, consortium of 8 academic and 2 industrial groups, 13 ESR recruited in 2015.

2016-2018: PI in the bilateral project with South Korea (prof. Sung You Hung, Ulsan) founded by Italian Ministry of Foreign Affairs (MAECI)

2019-2022: Partner of the MSCA-ETN project BactiVax

Dissemination, public engagement

International Congress 7th ECBS-LS (EuChems and EU Openscreen), Milano, 14-16 April 2021
International Congress MicrobiotaMi 2020, Milano 3-5 Feb 2020 
International congress MicrobiotaMi 2018, 5-7 November 2018 
Organizer of the workshop “Glycoscience: at the interface between Chemistry and Biology”Milano 12 July 2017
Organizer of the International Meeting “Molecular Aspects in the Host-Microbe dialogue”, Napoli 5-7 June 2017
Organizer of Horizon Chemistry 2014, 24 Jan 2014
Organizer of the Satellite Meeting to the 15th International Congress of Immunology (Milano, 2013), entitled “Endotoxin, TLR4 signalling and beyond”, Cinisello Balsamo (MI), 21 Aug 2013.
- Organizer of the SCI-sponsored congress: “Science and Art”, Milano, 4-6 May 2011.
- Organizer of the one-day congress HorizonChem 2014, 24 January 2014, University of Milano Bicocca.
-Organizer of the one-day congress “La Chimica in Bicocca incontra l’Industria”, 16 June 2016, Aula Magna University of Milano Bicocca.
-- Organizer of the European PhD Summer School, Milano 22-24 September 2015,
- Organizer of the EU Dissemination event “The wonderful journey of a molecule in our body: from drugs to functional food” 24 September 2015, EXPO Milano -Conference Room – MEDIA CENTER (in front of Pavilion Zero, TRIULZA entrance)

Positions and roles

Delegate for the Rector forthe foundation u4i

Delegate for the Rector for the foundation Carlo Erba


Also visit his  paintings site